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Please use this identifier to cite or link to this item: http://hdl.handle.net/1860/3053

Title: Optimization of medical guidewires through controllability matrix
Authors: Burns, Jason
Keywords: Mechanical engineering;Medical instruments and apparatus;Catheterization
Issue Date: 11-Jun-2009
Abstract: The procedure of catheterization with the assistance of guidewires is a very common practice in the medical field currently. This procedure can occur during many different types of treatments, for example catheterization can be used for draining fluids in the body, direct measurement of blood pressure in various arteries or veins, or for balloon angioplasty and stenting (Rutherford, 2005). Guidewire construction is currently viewed as more of an art than a science, with company secrets leading to mysticism surrounding the manufacture of these devices. This paper’s goal is to use a mathematical approach to model a guidewire and then analyze its properties, leading to the ability to optimize the manufacturing of medical guidewires. The first section describes the current state of guidewire technology with a critical review of several products currently on the market. The following section has an overview of controllability and observability theory and how this can apply to the manufacture ofcurrent guidewires and to the creation of the next generation active catheters and guidewires. The third section details the finite element-based modeling which will be employed in the analysis. Following this, the results are displayed. This work shows that using the controllability of a dynamic model of a guidewire can lead to optimized design points for manufacturing. Lastly, the expected benefits of this work as well as future work to be conducted are discussed.
URI: http://hdl.handle.net/1860/3053
Appears in Collections:Drexel Theses and Dissertations

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