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Please use this identifier to cite or link to this item: http://hdl.handle.net/1860/979

Title: Multi-site analysis of dopamine uptake in the somatosensory cortex
Authors: Khair, A.
Randall, C. L.
Moxon, Karen A.
Keywords: Neuroengineering
Issue Date: 2006
Citation: Poster presented at Biomedical Technology Showcase 2006, Philadelphia, PA. Retrieved 18 Aug 2006 from http://www.biomed.drexel.edu/new04/Content/Biomed_Tech_Showcase/Poster_Presentations/Moxon_2.pdf.
Abstract: Voltammetry has been used as a method to measure the concentration of monoaminergic neurotransmitters in-vivo. Studies have shown that the concentration of neurotransmitters, such as dopamine, varies across small regions of the brain (less than 1mm). To study the varying concentration of dopamine, a multi-site electrode would be beneficial. Therefore, the recording sites of our ceramic-based multi-site electrode were coated with carbon and deployed in the somatosensory cortex of a rat. Known concentrations of dopamine were pressure injected and the diffusion curve, which is the change in concentration over time, was recorded. The results show that the in-vivo data does not follow the prediction of the model providing an interesting insight to the uptake of monoamines across the different layers of the somatosensory cortex.
Description: Item from the Biomedical Technology Showcase held July 20, 2006 at Drexel University's Bossone Research Enterprise Center.
URI: http://hdl.handle.net/1860/979
Appears in Collections:Biomedical Technology Showcase, 2006

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