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Multi-site analysis of dopamine uptake in the somatosensory cortex
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|Title: ||Multi-site analysis of dopamine uptake in the somatosensory cortex|
|Authors: ||Khair, A.|
Randall, C. L.
Moxon, Karen A.
|Issue Date: ||2006 |
|Citation: ||Poster presented at Biomedical Technology Showcase 2006, Philadelphia, PA. Retrieved 18 Aug 2006 from http://www.biomed.drexel.edu/new04/Content/Biomed_Tech_Showcase/Poster_Presentations/Moxon_2.pdf.|
|Abstract: ||Voltammetry has been used as a method to measure the concentration of monoaminergic neurotransmitters in-vivo.
Studies have shown that the concentration of neurotransmitters, such as dopamine, varies across small regions of
the brain (less than 1mm). To study the varying concentration of dopamine, a multi-site electrode would be
beneficial. Therefore, the recording sites of our ceramic-based multi-site electrode were coated with carbon and
deployed in the somatosensory cortex of a rat. Known concentrations of dopamine were pressure injected and the
diffusion curve, which is the change in concentration over time, was recorded. The results show that the in-vivo data
does not follow the prediction of the model providing an interesting insight to the uptake of monoamines across the
different layers of the somatosensory cortex.|
|Description: ||Item from the Biomedical Technology Showcase held July 20, 2006 at Drexel University's Bossone Research Enterprise Center.|
|Appears in Collections:||Biomedical Technology Showcase, 2006|
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