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Multi-site analysis of dopamine uptake in the somatosensory cortex
Please use this identifier to cite or link to this item:
http://hdl.handle.net/1860/979
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| Title: | Multi-site analysis of dopamine uptake in the somatosensory cortex |
| Authors: | Khair, A.
Randall, C. L.
Moxon, Karen A. |
| Keywords: | Neuroengineering |
| Issue Date: | 2006 |
| Citation: | Poster presented at Biomedical Technology Showcase 2006, Philadelphia, PA. Retrieved 18 Aug 2006 from http://www.biomed.drexel.edu/new04/Content/Biomed_Tech_Showcase/Poster_Presentations/Moxon_2.pdf. |
| Abstract: | Voltammetry has been used as a method to measure the concentration of monoaminergic neurotransmitters in-vivo.
Studies have shown that the concentration of neurotransmitters, such as dopamine, varies across small regions of
the brain (less than 1mm). To study the varying concentration of dopamine, a multi-site electrode would be
beneficial. Therefore, the recording sites of our ceramic-based multi-site electrode were coated with carbon and
deployed in the somatosensory cortex of a rat. Known concentrations of dopamine were pressure injected and the
diffusion curve, which is the change in concentration over time, was recorded. The results show that the in-vivo data
does not follow the prediction of the model providing an interesting insight to the uptake of monoamines across the
different layers of the somatosensory cortex. |
| Description: | Item from the Biomedical Technology Showcase held July 20, 2006 at Drexel University's Bossone Research Enterprise Center. |
| URI: | http://hdl.handle.net/1860/979 |
| Appears in Collections: | Biomedical Technology Showcase, 2006
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